C gc c

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Actual: This process is the basis for the use of exogenous GC-C agonists such as linaclotide for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). Because GC-C agonists have limited use in pediatric patients, there is a need for alternative cGMP-elevating agents that are effective in the
4.7 rating 2025-04-23
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by G Hannig 2024 Cited by 51Activation of guanylate cyclase-C (GC-C) expressed predominantly on intestinal epithelial cells by guanylin, uroguanylin or the closely related GC-C agonist

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Trulance (plecanatide) is a guanylate cyclase-C (GC-C) agonist. GC-C is a protein that works in the intestines. Trulance (plecanatide) activates GC-C, which helps raise the amount of fluid in your intestines and speed up the movement of food through your gut. These actions soften stool, relieve belly pain, and help you have regular bowel movements.

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by H Prasad 2024 Cited by 13Receptor Guanylyl Cyclase C (GC-C) was initially characterized as an important regulator of intestinal fluid and ion homeostasis.

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antibiotics, chloride channel activators, guanylate cyclase C (GC-C) Dicyclomine hydrochloride (Bentyl) View full drug information.

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Background: Intestinal GC-C/cGMP pathway may be involved in visceral hypersensitivity and fluid secretion in irritable bowel syndrome (IBS). The guanylcyclase C

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GC-C Guanylyl cyclase C, an enzyme Prodelphinidin B3 (Gallocatechin 4→8 catechin dimer), a condensed tannin. Disambiguation icon.

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Linzess contains linaclotide which belongs to the class of drugs called guanylate cyclase-C agonists. The guanylate cyclase type-C (GC-C) receptor is located on the luminal surface of the intestine. Linaclotide works to treat IBS-C, CIC, and FC by stimulating the GC-C receptor to increase fluid secretion, which softens stools and stimulates

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with gastroparesis in the first half of 2024. ○. IW-3718: gastric LINZESS is the first and only guanylate cyclase-C (GC-C) agonist

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by S Amarachintha 2024 Cited by 17The guanylate cyclase C (GC-C) receptor regulates electrolyte and water secretion into the gut following activation by the E. coli

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