Is baclofen anticholinergic
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The answer is yes. Some muscle relaxers, such as cyclobenzaprine and baclofen, have anticholinergic effects. Anticholinergics block the action
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The Anticholinergic Burden (ACB) score is useful to raise awareness of the anticholinergic Baclofen. Cetirizine. Loratidine. Cimetidine. Loperamide.
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anticholinergic delirium. Case reports also describe its use in the reversal of respiratory depression caused by baclofen overdose. baclofen therapy.
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Higher anticholinergic adults due to anticholinergic effects (especially cyclobenzaprine), risk of sedation, and risk of fractures baclofen, tizanidine.
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Other Anticholinergic Drugs (with Lesser Anticholinergic Effect) Baclofen; Carisoprodol (Soma); Cetirizine (Zyrtec); Cimetidine (Tagamet)
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Baclofen. Diazepam. Methocarbamol. Analgesia. Opiates. Paracetamol and NSAIDs The anticholinergic risk scale and anticholinergic adverse effects in older
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For example, baclofen is moderately anticholinergic on the Anticholinergic Risk Scale (Rudolph et al, 2024) but is not on Chew's scale (Chew et al, 2024).
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For a discussion of anticholinergic toxicity, see Anticholinergics. Although baclofen, and several atypical antipsychotic (olanzapine, clozapine
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Higher anticholinergic adults due to anticholinergic effects (especially cyclobenzaprine), risk of sedation, and risk of fractures baclofen, tizanidine.
As for everyone else ... life keeps adding on the 'happy' {sarcasm}.
My neurologist decided to prescribe a more powerful tool to manage the pain in my feet. So, he gave me a foot cream. What wasn't obvious was the non-prescribed 'side effects' of the foot cream which included ... (sigh) ...
Well, as my feet have been hurting like sons-a-bitches, I was slathering that cream on three and four times a day. It had minimal positive effect which was leagues ahead of the pain I was going through. Besides, it was foot cream. What was the worse that could happen?
Baclofen (2%) ~ [Lightheadedness or fainting, trouble seeing, severe tiredness, weakness],
Cyclobenzaprine (2%) ~ [Anxiety, restlessness, seeing or hearing things that are not there, severe drowsiness, fainting, or confusion],
Diclofenac (3%) ~ [Sudden or severe headache, or problems with vision, speech, or walking],
Gabapentin (6%) ~ [Behavior problems, aggression, restlessness, trouble concentrating, moodiness (especially in children), problems with coordination, shakiness, unsteadiness, unusual moods, or behaviors, thoughts of hurting yourself, feeling depressed, dizziness, drowsiness, sleepiness, tiredness],
Lidocaine (2%) ~ [which, somewhat stunningly, isn't trying to fuck with my head]
So I've been staggering around in a semi-lucid state for the past several days, unable to figure out why I couldn't do much, if any, writing. It took me complaining to my wife to provide some clarity.
I repeat - it is freaking foot cream!
I've stopped with the foot-crack and am back to dealing with the pain. Hopefully I'll be back to writing soon too.
James aka FinalStand