effects of some antituberculous and anti-leprotic drugs on CATHEPSINS B, H AND L. Ramesh C. Kamboj, Neera Raghav, Ashwani Mittal, Shiwani Khurana, Rachna Sadana and
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The elimination of leprosy has been possible with the available anti-leprotic drugs. However, the lepra reactions usually occur months or years after multi-drug therapy completion, and continue to be a formidable challenge mainly owing to its role in causing nerve damage and disability. Corticosteroids are commonly used but they lead to systemic complications, and hence require dose reduction
The document discusses anti-leprotic drugs used to treat leprosy, including dapsone, clofazimine, rifampin, ethionamide, ofloxacin, minocycline, and clarithromycin. It provides details on the mechanisms of action, pharmacokinetics, uses, and adverse effects of these drugs.
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The elimination of leprosy has been possible with the available anti-leprotic drugs. However, the lepra reactions usually occur months or years after multi-drug therapy completion, and continue to be a formidable challenge mainly owing to its role in causing nerve damage and disability. Corticostero
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