Geographic atrophy drugs

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Actual: Experts discuss pegcetacoplan and avacincaptad pegol, the new drugs for treatment of geographic atrophy.
4.3 rating 2025-04-24
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The approval marks the first and only treatment for geographic atrophy, a leading cause of blindness.

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Syfovre and Izervay must not be used with other geographic atrophy drugs for commercial members, starting Nov. 24.

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Pegcetacoplan (Geographic Atrophy) (Local) (Monograph). Drug class: Macular Degeneration Agents. Medically reviewed by Drugs.com on Jun 10

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Until earlier this year, there were no Food and Drug Administration (FDA) approved treatments available to patients with geographic atrophy. In February 2024, Syfovre (pegcetacoplan) became the first FDA-approved treatment for geographic atrophy, and now, the FDA has approved a second medication, Izervay (avacincaptad pegol).

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The Geographic Atrophy market in the United States is estimated to be ~$1 billion. Which therapies are leading the geographic atrophy market? Immune response-

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drugs, over-the-counter medicines and natural products. This material is Discover a treatment option for Geographic Atrophy. Close.

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effect increased over time. The drug works by inhibiting parts of the body's inflammatory response that contribute to geographic atrophy. SYFOVRE is

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3.3 No treatment for geographic atrophy Geographic atrophy involving the fovea is responsible for approximately 10% of all AMD-related visual loss of 20/200 or

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Izervay was shown to slow progression of geographic atrophy, a leading cause of irreversible blindness.

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