Titration or conversion back to amlodipine (n=19) Amlodipine 5 mg to felodipine 5 mg: Increase in concurrent fosinopril dosage: Amlodipine 7.5 mg to nifedipine CC 30 mg:
release nifedipine (Procardia XL) were converted to either amlodipine (Norvasc) or felodipine (Plendil) from September 2024 through February 2024. The study drugs were defined as extended-release nifedipine, amlodipine, and felodipine. The conversion date was defined as the first record of a filled pre- scription for either amlodipine or
The costs presented were limited to the annual cost of amlodipine and the cost-savings arising from the conversion to felodipine. The calculated annual acquisition cost of amlodipine for the entire group was $26,809. The conversion to felodipine, taking account of the higher mean doses of this drug, resulted in annual cost-savings of $15,888.
Conversion from amlodipine to other calcium channel blockers resulted in statistically significant reductions in diastolic blood pressure and MAP, and was safe as well as cost-effective. Conversion to calcium channel antagonists other than felodipine or less than equal dosages of felodipine may require dosage titration.
Titration or conversion back to amlodipine (n=19) Amlodipine 5 mg to felodipine 5 mg: Increase in concurrent fosinopril dosage: Amlodipine 7.5 mg to nifedipine CC 30 mg:
Conversion from amlodipine to other calcium channel blockers resulted in statistically significant reductions in diastolic blood pressure and MAP, and was safe as well as cost-effective. Conversion to calcium channel antagonists other than felodipine or less than equal dosages of felodipine may requ
conversion. em Amlodipine /em - calcium Pharmacology . Amlodipine Dihydropyridines (amlodipine, felodipine, nifedipine. www.youtube.com.
washout period is required for conversion between an ARB and an ARNI. The However, amlodipine and felodipine may be considered for other indications.
by MS McDonagh 2024 Cited by 13Dihydropyridines include amlodipine, bepridil, felodipine, isradipine, nicardipine, nifedipine, and nisoldipine. conversion to normal sinus rhythm. One
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