Purine analogues drugs

Allopurinol is a purine analogue and competitive inhibitor of xanthine oxidase, a key enzyme in the production of uric acid by purine metabolism

Xanthine oxidase inhibitors are of two kinds: purine analogues and others. Purine analogues include allopurinol, oxypurinol, and tisopurine. Others include febuxostat, topiroxostat, and inositols (phytic acid and myo-inositol).

It belongs to a class of antiviral drugs known as synthetic purine deoxynucleoside analogues. This class is also sometimes referred to as

Antimetabolite drugs are commonly used to treat leukemia, cancers of the purine analogues – mimic the structure of metabolic purines, the larger

Allopurinol is a purine analogue that is subject to being metabolized by many enzymes involved in purine and pyrimidine synthesis metabolism, whereas febuxostat

Prednisone, Pregabalin, Pregnadien Derivatives, Pregnen (4) Derivatives Psychostimulants, Agents Used For Adhd And Nootropics, Purine Analogues, Purine

by S Spurgeon 2024 Cited by 75Cladribine was synthesized as a purine analogue drug that inhibited adenos- photoxic drugs including other purine nucleoside analogues, cladribine

Purine analogues mimic this condition by irreversibly binding to adenosine deaminase or by fostering resistance to deamination in the purine

by CC Erhardt 2024 Cited by 3The drugs commonly used are cyclophosphamide and chlorambucil (alkylating agents), azathioprine (purine analogue) and methotrexate (folic acid analogue). A