The patient was only temporarily responsive to IV metoprolol and wasn't responsive whatsoever to PO metoprolol tartrate or PO amiodarone. I
IV, intravenous; PO, oral; SR, sinus rhythm. Eur Heart J. 2024 Oct PO amiodarone 600 mg in 3 divided doses vs. IV amiodarone 5mg/kg
Loading with amiodarone can be done in several ways – IV, PO, IV followed by PO, or IV and PO together. The loading regimen employed depends
IV, intravenous; PO, oral; SR, sinus rhythm. Eur Heart J. 2024 Oct;15 PO amiodarone 25.7 mg/kg vs. IV amiodarone 3-5 mg/kg bolus
afib or ≥2 failed attempts to wean from IV amiodarone. ▫ ≤ 24hours on IV amiodarone: start mg po Q12h. ▫ ≥ 48hours on IV amiodarone: start 200mg po q12h.
Amiodarone increases PO digoxin serum concentrations by ~70% and IV digoxin by ~17%; measure digoxin levels before initiating amiodarone and reduce PO
PO amiodarone 25.7 mg/kg vs. IV amiodarone 3-5 mg/kg bolus then mg/kg over 24 h. No difference in conversion to SR between PO and IV.
by U Khanderia 2024 Cited by 19May start amiodarone IV or PO. 6. Amiodarone 150 mg IV bolus (may repeat). 7. Amiodarone load: IV: 1 mg/min x 6 hr, then 0.5 mg/min x 18 hr, then 200 mg PO
Amiodarone IV Dosing Amiodarone PO dosing in hospital. After converts to NSR or after 24 hrs, 400mg PO BID up to 10g load (includes IV), then 200mg daily.
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