Are platinum drugs renally cleared

population models by renally cleared small‐molecule antibacterial drugs in Chinese renal impairment patients. 2

platinum within 24 hours. Most of the drug is excreted in the first 6 hours. The total body and renal clearance of free ultrafilterable platinum.

The other one important aspect of platinum resistance is that oxaliplatin is the only platinum drug recommended for platinum resistance current .The aim is to choose the appropriate platinum drugs used for chemotherapy, which could help to reduce adverse drug reactions in important target organs and reduce the occurrence of platinum resistance

For renally excreted drugs with a narrow therapeutic index, the total daily platinum. compounds of nephrotoxicity and possibly of ototoxicity.

kidneys and the degree of RI. For drugs cleared primarily by renal excretion (e.g, gabapentin and pregabalin), even a mild degree of renal

In patients with impaired renal function, renal clearance and total body clearance of platinum are reduced. In patients undergoing hemodialysis, t values for total and ultrafilterable platinum are increased compared with values in individuals with normal renal function. Stability Storage Parenteral Injection Concentrate

The first drug is usually a platinum product platinum product platinum is a metal and is an important ingredient in many anti-cancer drugs, either cisplatin

by M Naganuma 2024 Cited by 11We evaluated the incidence of renal impairment as adverse events are related to the administration of platinum compounds using the Japanese Adverse Drug Event

Newer platinum agents such as this medication is not renally cleared and does not require dose adjustments in patients with renal insufficiency. Bortezomib should be given after dialysis in