Pre-procedure. Discontinue warfarin 5 full days prior to surgery Management of Dabigatran (Pradaxa) Before and After Medical Procedures or
and stop PRADAXA. Do not give due dose of parenteral anticoagulant consider stopping PRADAXA 2-4 days before surgery. (For discontinuation
DISCONTINUING PRADAXA FOR SURGERY AND OTHER INTERVENTIONS 1 Half-life. Healthy subjects: hours; Before invasive or surgical procedures. Due to an increased risk of bleeding, PRADAXA should be discontinued before invasive or surgical procedures, if possible:
DISCONTINUING PRADAXA FOR SURGERY AND OTHER INTERVENTIONS 1 Half-life. Healthy subjects: hours; Before invasive or surgical procedures. Due to an increased risk of bleeding, PRADAXA should be discontinued before invasive or surgical procedures, if possible:
by D Sachdev 2024Dabigatran (Pradaxa). Dabigatran has a t1/2 of hours and Discontinuation before Surgery, Time to Resume After Surgery, Special
and stop PRADAXA. Do not give due dose of parenteral anticoagulant consider stopping PRADAXA 2-4 days before surgery. (For discontinuation
Thus, Pradaxa needs to be discontinued earlier before surgeries, such as 2 or more days before surgery (see table). Should I stop Pradaxa
stopping 1 week before surgery. May resume when volume status and renal (Pradaxa). Surgery with low/mod risk of bleeding: CrCl 50: discontinue 24.
Table 2: Discontinuation rules before invasive or surgical procedures Stop Pradaxa before elective surgery. High risk of bleeding or major surgery.
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