36 trials (7 tizanidine vs. baclofen, 2 tizanidine vs. diazepam, 1 baclofen vs. diazepam, 1 dantrolene vs. diazepam) 1359 patients overall: Good. Included studies of fair or poor quality. Tizanidine more effective than baclofen for muscle strength in 2 out of 7 head-to-head trials, otherwise no significant differences in efficacy.
tizanidine compared with baclofen. Acta. Neurol (2024) Tizanidine vs baclofen in the treatment of spasticity in patients with multiple sclerosis.
36 trials (7 tizanidine vs. baclofen, 2 tizanidine vs. diazepam, 1 baclofen vs. diazepam, 1 dantrolene vs. diazepam) 1359 patients overall: Good. Included studies of fair or poor quality. Tizanidine more effective than baclofen for muscle strength in 2 out of 7 head-to-head trials, otherwise no significant differences in efficacy.
Tizanidine Vs Baclofen Vs Cyclobenzaprine. There is no definitive answer as to which medication is best for treating muscle spasms. All three medications tizanidine, baclofen, and cyclobenzaprine are effective at relieving muscle spasms and pain.
36 trials (7 tizanidine vs. baclofen, 2 tizanidine vs. diazepam, 1 baclofen vs. diazepam, 1 dantrolene vs. diazepam) 1359 patients overall: Good. Included studies of fair or poor quality. Tizanidine more effective than baclofen for muscle strength in 2 out of 7 head-to-head trials, otherwise no significant differences in efficacy.
Tizanidine vs cyclobenzaprine Tizanidine vs baclofen Tizanidine vs Drugs.com provides accurate and independent information on more than 24,000
36 trials (7 tizanidine vs. baclofen, 2 tizanidine vs. diazepam, 1 baclofen vs. diazepam, 1 dantrolene vs. diazepam) 1359 patients overall: Good. Included studies of fair or poor quality. Tizanidine more effective than baclofen for muscle strength in 2 out of 7 head-to-head trials, otherwise no significant differences in efficacy.
No difference between baclofen and placebo. Lataste 2024 43: Assess the comparative efficacy of tizanidine compared to other anti-spastic agents. Tizanidine Baclofen Diazepam a: 20 trials (14 vs. baclofen, 6 vs. diazepam) 385 patients on tizanidine, 392 on baclofen or diazepam: Poor.
36 trials (7 tizanidine vs. baclofen, 2 tizanidine vs. diazepam, 1 baclofen vs. diazepam, 1 dantrolene vs. diazepam) 1359 patients overall: Good. Included studies of fair or poor quality. Tizanidine more effective than baclofen for muscle strength in 2 out of 7 head-to-head trials, otherwise no significant differences in efficacy.
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