Losartan metabolite
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After a losartan dose, the body converts it to an active metabolite. The metabolite provides much of losartan's blood pressure lowering
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After a losartan dose, the body converts it to an active metabolite. The metabolite provides much of losartan's blood pressure lowering
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metabolite. The pharmacokinetics of losartan and its active metabolite are linear with oral losartan potassium doses up to 200 mg. Following oral
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After a losartan dose, the body converts it to an active metabolite. The metabolite provides much of losartan's blood pressure lowering
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losartan and its active metabolite are approximately equal, the AUC (area under the curve) of the metabolite is about 4 times as great as that of losartan.
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After a losartan dose, the body converts it to an active metabolite. The metabolite provides much of losartan s blood pressure lowering effects. The losartan half-life is about 2 hours and the metabolite half-life is 6 to 9 hours. This means it can take a couple of days to clear losartan and its metabolite from your system.
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After a losartan dose, the body converts it to an active metabolite. The metabolite provides much of losartan's blood pressure lowering
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The affinity of losartan and its metabolite is about fold greater for the AT1 receptor than for the AT2 receptor. Neither losartan or its metabolite
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losartan efficiently to the active metabolite. Mean peak concentrations of losartan occur at about one hour, and that of its active metabolite
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