Acyclovir renal

☑️@acyclovir_renal · 1201 subscribers · Content 18+ 🔞

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Actual: Within 48 h of commencing intravenous acyclovir, there was a marked deterioration in renal function. On stopping acyclovir therapy, renal function improved back to baseline. No other cause for deterioration in renal function was identified. The most likely cause for acute renal failure was secondary to acyclovir therapy.

4.6 rating 2025-04-25

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Comments

User5246

like caries, renal calculi, after bleaching, cancer, yankees fan, such stories, donald the liar trump, aaaa , well that may be the ones.

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User8368

Someone with end-stage renal disease should not be eating pizza. The sodium load could throw them into heart failure and kill them. I know this is all fantasy but the odds of this meeting are so ridiculously low that it made shambles of any shred of believability. Congrats on your win nonetheless.

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User6112

Five of my immediate family have had renal cancer. Mother, six months, one brother four years and then lungs, one brother survived, one nephew at forty nine after surviving an operation at thirty six, and another nephew holding on. We are familiar with NIH and agree that they are generous and giving people. Thank for the article ever though it was tough to read in parts.

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User5109

Not the story I expected. We have dear friends of over 40 years going through renal cancer. Her struggles with the cancer and his in feeling like he's loosing her. To many of us have gone through this. My wife the breast cancer survivor, my family, her family and to many friends. Bless those in the medical profession for their dedication.
Thank you for sharing.

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User5817

Actually a dum story. Stage three renal or kidney failure is not painful and the medical profession will not do a kidney transp,ant until stage five and the patient is on dialysis.
Also you dont bail out of a plane at 2000 ft to skydive. That is less than 1/2 mile high. You would ied very quickly. Story is not written well.

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User1211

make that Dr. Bob ...if only to show proper respect. :-)
I am most pleased to hear that you seem to have beaten the big C. I'm an 11-year survivor too (Renal Cell Carcinoma, caught unusually early in my case - only cost me 1/3rd of a kidney and some scars). Were the hand/coordination symptoms you were reporting previously due to the treatment regimen, or something else?
In any case, I'm very happy to hear of your progress, but am curious about the cancelling/suspension of the study group you were part of. What phase was the study in? It certainly seems that they were doing _something_ right, even if something else was bad wrong.
Hope you're feeling much better, if not already, then soon.
- GrandPaM

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Valacyclovir or acyclovir neurotoxicity commonly develops in patients with an impaired renal function, implying a role of a declined renal clearance mediated accumulation of acyclovir and/or its metabolites in the bloodstream. 3,4 Given that the renal clearance of acyclovir absolutely exceeds that of creatinine, indicating that renal tubular

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renal function. Probenecid decreases acyclovir renal clearance by approximately 32%, presumably by inhibiting tubular secretion of acyclovir.[ ] The

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by KC Zachary Cited by 5INDICATIONS FOR ACYCLOVIR DOSE ADJUSTMENTS Reduced renal function Obesity Acyclovir resistance TOXICITY Acute renal failure

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186 Citations Rapidly progressive acute renal failure due to acyclovir: case report and review of the literature. Acyclovir‐induced acute renal failure.

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Dosage precautions Acyclovir has been associated with renal Dosage adjustment is recommended when using Acyclovir in patients with renal

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Acyclovir-induced renal failure is caused by precipitation of acyclovir crystals within the renal tubules, leading to obstructive nephropathy

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by DW Huntjens 2024 Cited by 13An important side effect of acyclovir is acute renal failure. Acyclovir-induced renal failure may be caused by intratubular deposition of acyclovir crystals

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by KC Zachary Cited by 5INDICATIONS FOR ACYCLOVIR DOSE ADJUSTMENTS Reduced renal function Obesity Acyclovir resistance TOXICITY Acute renal failure

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