Drugs to increase hdl

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Actual: However, low levels of HDL cholesterol have not been established as causative of this increase in risk. (See 'Low HDL cholesterol as an ASCVD risk factor' below and 'Effect of increasing HDL cholesterol on clinical outcome' below.) This topic will address clinical aspects of abnormal HDL (the particle) and HDL cholesterol.
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by AA Much 2024 Cited by 3Pharmacological approaches to increase HDL Cholesterol (HDL-C) failed to improve cardiovascular outcomes. drugs and had their HDL-C level documented at each

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HDL cholesterol can be a bad thing, drug companies remain invested in identifying drugs to increase HDL cholesterol. Merck recently

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However, HDL cholesterol levels may be increased in some genetic disorders. If a high HDL level is found in a person who is not taking lipid-lowering drugs

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However, low levels of HDL cholesterol have not been established as causative of this increase in risk. (See 'Low HDL cholesterol as an ASCVD risk factor' below and 'Effect of increasing HDL cholesterol on clinical outcome' below.) This topic will address clinical aspects of abnormal HDL (the particle) and HDL cholesterol.

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5 So, although niacin increases HDL-C, it has minimal to no effect on increasing HDL-P. Niacin is an LDL-lowering drug, specifically lowering LDL particle

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decrease LDL (bad) cholesterol and triglyceride levels. increase HDL (good) cholesterol levels. decrease the Total Cholesterol/HDL-Cholesterol Ratio (TC: HDL-C

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There are several basic mechanisms by which a drug can raise HDL cholesterol: an increase in the uptake of cholesterol from tissues by HDLs; an increase in the transfer of cholesterol from other lipoproteins to HDLs; a reduction of the rate of transfer of cholesteryl esters from HDLs to the liver; and a reduction of cholesteryl ester transfer

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There are several basic mechanisms by which a drug can raise HDL cholesterol: an increase in the uptake of cholesterol from tissues by HDLs; an increase in the transfer of cholesterol from other lipoproteins to HDLs; a reduction of the rate of transfer of cholesteryl esters from HDLs to the liver; and a reduction of cholesteryl ester transfer

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Conclusions: Torcetrapib was associated with a substantial increase in HDL and a decrease in LDL. This drug also increased blood pressure and

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