Drug characteristics are summarized in Table 1 [13, 43]. Contact activation inhibitor and factor XI antibody, AB023, produces safe, dose-dependent anticoagulation
by J Presume 2024 Cited by 4The pursuit of alternative drugs has honed in on factor XI/XIa inhibitors drug discovery efforts that led to the direct factor Xa inhibitor
Factor XI inhibition may provide anticoagulation, with a low risk of bleeding, and several factor XI inhibitors, including fesomersen, an antisense
We have different types of factor XI inhibitors. We have an antisense oligonucleotide (fesomersen, Ionis) that reduces the synthesis of factor
Asundexian, in development by Bayer, is a direct, potent inhibitor of activated coagulation factor XI. It is dosed once daily and has a mean
Pharmacological and clinical appraisal of factor XI inhibitor drugs. Journal: European Heart Journal - Cardiovascular
oral anti-clotting medication or anticoagulant rivaroxaban. It is the longest and largest trial to-date comparing factor XI inhibitors to
Abelacimab is an injectable, monoclonal antibody, categorized as a factor XI inhibitor, that has the potential to prevent the clots that
New DVT treatment includes new drugs such as tissue factor pathway inhibitors (TFPIs), nematode anticoagulant peptides (NAPc2) and factor XI
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