Arbaclofen

Arbaclofen extended-release tablets twice-daily are safe and effective for the treatment of spasticity in multiple sclerosis.

AAp-At Apalutamide Apaziquone Apixaban Apomorphine Apremilast Aprepitant Aprocitentan Arbaclofen Arformoterol Inhalation Argatroban

This study will examine the safety and efficacy of arbaclofen vs. placebo on social function in children and adolescents with Autism

A phase 2 randomized, placebo-controlled, crossover trial found that the GABA-B agonist arbaclofen improved social avoidance symptoms in FXS. A pilot open-label trial of arbaclofen suggested similar benefits in ASD. We therefore evaluated arbaclofen in a randomized, placebo-controlled, phase 2 study of 150 participants, aged 5 21 years, with ASD.

Arbaclofen ER (brand name, Ontinua ER) is an extended release formulation of arbaclofen, a compound similar to the muscle relaxant baclofen that is approved to treat spasticity (muscle stiffness

Avoid or Use Alternate Drug. arbaclofen. hydrocodone, arbaclofen. Either increases toxicity of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Profound sedation, respiratory depression, coma, and death may result if coadministered.

The goal was to find research studies that address the use of arbaclofen in patients or models of ASD. Arbaclofen was not compared to any other treatment and all study designs were considered. The primary goal was to consider improvement in any symptom or pathological marker associated with ASD as a result of arbaclofen treatment.

CHEBI: - Arbaclofen ; Stars, This entity has been manually annotated by a third party. ; Submitter, MetaboLights.

Arbaclofen, for example, is the R-enantiomer of racemic baclofen (a muscle relaxant). From: Pharmacology Therapeutics, 2024.