Zafirlukast was the first antileukotriene drug to be approved by the FDA for the treatment of asthma. Definite limitations were imposed on its clinical
Claesson, Asthma and leukotrienes: antileukotrienes as novel antiasthmatic drugs, J Intern Med, № 245, с. Wenzel, Antileukotriene drugs in the management of
The arguments for and against antileukotriene drugs therapy in the treatment of obstructive lung diseases and rhinitis are discussed.
corticosteroids β-agonists muscarinic antagonists methylxanthines antileukotrienes omalizumab.
by AV Kupkina 2024drugs. Antileukotriene drugs are considered as a second line of therapy as an alternative to corticosteroids in the treatment of mild persistent asthma and
^ Jump up to: Drugs@FDA: FDA Approved Drug Products. U.S. Food Drug Antileukotriene Drugs: Clinical Application, Effectiveness and Safety.
Purpose of review: Despite profound effects of leukotrienes in experimental models, clinical responses to antileukotriene drugs are highly heterogeneous. This review discusses recent advances concerning the molecular mechanisms of antileukotrienes as well as their efficacy in various clinical scenarios and patient groups.
by A Coreno 2024 Cited by 132of drugs, as well as the relative potencies of the antileukotriene mental designs clearly show that the antileukotriene drugs work, they do not
antileukotriene drugs have yielded variable results. For example, some studies in patients with moderate persistent asthma or aspirin
Comments