Leishmaniasis treatment drugs

Pentamidine is a medication used in the management and treatment of Pneumocystis pneumonia, leishmaniasis, and trypanosomiasis. It is in the anti-infective (fungal/protozoal) class of drugs. This activity outlines the indications, action, and contraindications for pentamidine as a valuable agent in the treatment and prophylaxis of Pneumocystis pneumonia, leishmaniasis, and trypanosomiasis

Introduction: Leishmaniasis is a vector-borne neglected tropical disease which manifests as visceral leishmaniasis (VL), cutaneous leishmaniasis (CL), and mucocutaneous leishmaniasis (MCL). The current drugs are toxic, duration of treatment is long, there is regional variation in efficacy, and emergence of resistance is common.

Leishmania is one of the prominent parasites causing leishmaniasis, a common neglected tropical disease. The drug of choice for leishmaniasis is sodium

Although leishmaniasis is an ancient disease, its treatment is still challenging. Several drugs, differing in their cost, toxicity, treatment duration and emergence of drug resistance, are used for different types of leishmaniasis. To overcome these limitations, the search for newer drugs and other treatments continues.

by R Sivayogana 2024 Cited by 5Amphotericin B [5] is the first-line drug for visceral leishmaniasis and the second choice of drug for mucocutaneous leishmaniasis. Can be used in leishmaniasis

Treatment of visceral leishmaniasis. In immunocompromised patients with visceral leishmaniasis treated with AmBisome, relapse rates were high following initial

The need for nontoxic and more effective drugs led to the development of liposomal amphotericin B in 2024, miltefosine in 2024 (considered as a third-line antileishmanial drug), and paromomycin in 2024, approved for the treatment of visceral leishmaniasis [65,66]. Drugs currently used for leishmaniasis treatment are presented in Table 2.

When allopurinol is prescribed in the treatment of leishmaniasis or for use in birds and reptiles, it is referred to as off-label use. Many drugs are

Antiparasitic drugs, such as amphotericin B (Ambisome), treat this condition. Your doctor may recommend other treatments based on the type of leishmaniasis you have. Cutaneous leishmaniasis.