Indomethacin in pregnancy
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Indomethacin Pregnancy and Breastfeeding Warnings. Brand names: Indocin, Indocin IV, Indocin SR, Tivorbex. Medically reviewed by Drugs.com. Last updated on . Pregnancy Warnings; Breastfeeding Warnings; Indomethacin Pregnancy Warnings. Contraindicated last trimester of pregnancy NSAIDs should be avoided at 20 weeks gestation and later
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indomethacin therapy (indomethacin treatment 48 hours) (LIT) stabilizes the cervical length (CL), successfully prolongs pregnancy in patients with short cervix
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Talk to your doctor if you experience any abdominal pain after taking indomethacin, particularly if the pain persists. NSAIDs such as indomethacin should not be used in the last 3 months of pregnancy; ask your doctor before using any medication during pregnancy.
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All three are pregnancy category B in the first and second trimester, and category D in the third trimester. The most studied NSAID in pregnancy is the prescription product indomethacin. Similar to the OTC products, indomethacin is also a pregnancy category B in the first trimester and D in the third trimester.
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Indomethacin Pregnancy Warnings Comments: -NSAID use in pregnancy prior to 20 weeks gestation should be based on a benefit-risk assessment;
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Pregnancy Among Women with Linked. Singleton Live Birth Deliveries (N Indocin indomethacin. Indocin SR indomethacin indomethacin indomethacin
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Indomethacin may harm the fetus and cause problems with delivery if it is taken around 20 weeks or later during pregnancy. Do not take indomethacin around or after 20 weeks of pregnancy, unless you are told to do so by your doctor. If you become pregnant while taking indomethacin, call your doctor.
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Indomethacin may harm the fetus and cause problems with delivery if it is taken around 20 weeks or later during pregnancy. Do not take indomethacin around or after 20 weeks of pregnancy, unless you are told to do so by your doctor. If you become pregnant while taking indomethacin, call your doctor.
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A mechanistic PBPK model adequately described the maternal and the fetal PK of indomethacin during pregnancy. As the pregnancy progresses, a modest decrease ( 32%) in systemic exposures in pregnant women and a 33% increase in fetal exposures to indomethacin were predicted. Higher fetal exposures in
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