Paliperidone vs risperidone

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Actual: The active substance in this medicine, paliperidone, is an antipsychotic medicine. Paliperidone is an active breakdown product (metabolite) of risperidone
4.4 rating 2025-04-27
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Plasma protein binding of paliperidone is 74% vs 90% in risperidone. Risperidone is mainly metabolized in the liver via cytochrome P450 2D6

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No significant differences were found between Quetiapine ER vs. quetiapine and risperidone; risperidone vs. clozapine and aripiprazole; olanzapine vs. paliperidone; risperidone LAI vs. paliperidone and paliperidone palmitate monthly LAI; and aripiprazole vs. aripiprazole monthly LAI. Withdrawal due to adverse events

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Risperidone to paliperidone (once-monthly). Formulation: depot to depot. Print. Stop risperidone. Paliperidone depot can be given on the day

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At steady state, the doses administered resulted in a similar exposure to paliperidone and the pharmacologically active fraction of risperidone (i.e. risperidone paliperidone), respectively. Eligible patients were randomized to either paliperidone extended-release 12 mg on days 1-6 or risperidone immediate-release 2 mg on day 1 and 4 mg on

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Efficacy and safety of the 3-month formulation of paliperidone palmitate vs paliperidone, risperidone, or to any excipients in INVEGA. Cerebrovascular

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peridone (Citrome, 2024; Paliperidone: new drug, 2024; Dolder et al, 2024; Dopheide, 2024). Clinical differences between paliperidone versus risperidone may stem from dif-ferent pharmacokinetic properties and different formulations (extended release vs. oral). Since paliperidone and risperidone display simple, competitive antagonism in

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No significant differences were found between Quetiapine ER vs. quetiapine and risperidone; risperidone vs. clozapine and aripiprazole; olanzapine vs. paliperidone; risperidone LAI vs. paliperidone and paliperidone palmitate monthly LAI; and aripiprazole vs. aripiprazole monthly LAI. Withdrawal due to adverse events

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Combining-Aripiprazole-Risperidone Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone). The combination

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The PANSS score was the primary efficacy outcome measure; there was no significant difference between the paliperidone and risperidone groups. DIEPSS and prolactin levels were significantly decreased from baseline in the paliperidone group compared to the risperidone group ( 3.1 vs. 0.5, respectively, p = 0.0002).

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