The loading dose of levetiracetam (Keppra) for status epilepticus isn't a knee-jerk 1gm. It's 60mg/kg of TBW to a max of 4.5gm.
Patient Assistance Program. Product(s) covered by program: Keppra (levetiracetam) tablets (max dose: 10/100, a total daily dose of 80 mg carbidopa and 800 mg
Properties, Phenytoin/ Fosphenytoin, Levetiracetam (Keppra) ; Dose, 20 mg/kg/PE (max 1500 mg), 1-4.5 g IV ( mg/kg) ; Administration, Max IV
dose of LEV XR (Keppra XR tablets, 500 mg and 750 mg) administered max,D and AUC24h,D and normalized per kg bodyweight (Cmax,DW and
The loading dose of levetiracetam (Keppra) for status epilepticus isn't a knee-jerk 1gm. It's 60mg/kg of TBW to a max of 4.5gm.
I'm at 1500 mg 2x/day, so 3000 mg of Keppra. My neuro says that's the max recommended dose. I was having frequent auras last year so she
Bioavailability of KEPPRA XR tablets is similar to that of the immediate-release KEPPRA tablets. The pharmacokinetics (AUC and C max) were shown to be dose proportional after single dose administration of 1000 mg, 2024 mg, and 3000 mg extended-release levetiracetam. Plasma half-life of extended-release levetiracetam is approximately 7 hours.
The loading dose of levetiracetam (Keppra) for status epilepticus isn't a knee-jerk 1gm. It's 60mg/kg of TBW to a max of 4.5gm.
At this site, Keppra was given safely given undiluted up to a max dose of 4,500 mg over 5 minutes. This study included over 900 patients with over 8,500 doses of undiluted Keppra given. 3,674 (43%) of doses were greater than 1,000 mg In conclusion, it is reasonable to give up to 4,500 mg of IVP Keppra undiluted over 5 minutes.
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