Acyclovir renal
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Valacyclovir or acyclovir neurotoxicity commonly develops in patients with an impaired renal function, implying a role of a declined renal clearance mediated accumulation of acyclovir and/or its metabolites in the bloodstream. 3,4 Given that the renal clearance of acyclovir absolutely exceeds that of creatinine, indicating that renal tubular
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Acyclovir-induced renal failure is caused by precipitation of acyclovir crystals within the renal tubules, leading to obstructive nephropathy
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Acyclovir-induced renal failure is caused by precipitation of acyclovir crystals within the renal tubules, leading to obstructive nephropathy
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22 References Influence of hemodialysis on acyclovir pharmacokinetics in patients with chronic renal failure. Acyclovir kinetics in end‐stage renal disease.
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commencing intravenous acyclovir, there was a marked deterioration in renal function. On stopping acyclovir therapy, renal function improved back to baseline. No other cause for deterioration in renal function was identified. The most likely cause for acute renal failure was secondary to acyclovir therapy.
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Within 48 h of commencing intravenous acyclovir, there was a marked deterioration in renal function. On stopping acyclovir therapy, renal function improved back to baseline. No other cause for deterioration in renal function was identified. The most likely cause for acute renal failure was secondary to acyclovir therapy.
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by DW Huntjens 2024 Cited by 13An important side effect of acyclovir is acute renal failure. Acyclovir-induced renal failure may be caused by intratubular deposition of acyclovir crystals
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Acyclovir-induced renal failure is caused by precipitation of acyclovir crystals within the renal tubules, leading to obstructive nephropathy
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by TH Htwe 2024 Cited by 24References Acyclovir-induced renal failure. Acyclovir treatment of the chronic fatigue syndrome. Rapidly progressive acute renal failure due to acyclovir:
Comments
Thank you for sharing.
Also you dont bail out of a plane at 2000 ft to skydive. That is less than 1/2 mile high. You would ied very quickly. Story is not written well.
I am most pleased to hear that you seem to have beaten the big C. I'm an 11-year survivor too (Renal Cell Carcinoma, caught unusually early in my case - only cost me 1/3rd of a kidney and some scars). Were the hand/coordination symptoms you were reporting previously due to the treatment regimen, or something else?
In any case, I'm very happy to hear of your progress, but am curious about the cancelling/suspension of the study group you were part of. What phase was the study in? It certainly seems that they were doing _something_ right, even if something else was bad wrong.
Hope you're feeling much better, if not already, then soon.
- GrandPaM