Oral standard-dose ibuprofen was more effective than oral paracetamol (P = .001). The ductus closed faster in the high-dose ibuprofen group than in the standard-dose group (median closure time 3.9
For a dog of Monty's size, the toxic dose of ibuprofen was calculated to be around 800mg of ibuprofen – that's the equivalent of just 4 standard
by ibuprofen 10 mg/kg/day for two doses compared with the standard-dose of ibuprofen 10 hemodynamically significant PDA closure compared to standard doses of
For a dog of Monty's size, the toxic dose of ibuprofen was calculated to be around 800mg of ibuprofen – that's the equivalent of just 4 standard
Standard vs. high-dose ibuprofen protocols. The standard-dose ibuprofen regimen for hs-PDA was administered intravenously once daily for 3 consecutive days (10 5 5 mg/kg/day).
per day; Ibuprofen compares favourably with gold standard treatment for Ibuprofen at doses 1,200mg daily, along with other NSAIDs
No difference in the safety profile with high-dose ibuprofen as compared to the standard-dose regimen was demonstrated. High-dose ibuprofen may significantly reduce PDA ligations. Comparison of standard versus high-dose ibuprofen for the treatment of hemodynamically significant patent ductus arteriosus in preterm infants
by K Hillier 2024 Cited by 5High-dose ibuprofen may significantly reduce PDA ligations. No difference in the safety profile with high-dose ibuprofen as compared to the standard-dose
Oral standard-dose ibuprofen was more effective than oral paracetamol (P = .001). The ductus closed faster in the high-dose ibuprofen group than in the standard-dose group (median closure time 3.9
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